Agrochemical Active Ingredients Testing
Active ingredients are important components of agrochemicals that express therapeutic, medicinal or biochemical effects on living matter. Agrochemicals, in particular pesticides, herbicides and insecticides, are formulated with inert or excipient chemicals that either modulate the adverse effects of active ingredients or act as transport vehicles. Understanding the biological activity of an active ingredient plays an important role in determining its viability and efficacy. The degree of biological activity of active ingredient usually indicates a proportional relationship between dosage concentration and beneficial effects, with a common correlation between increased adverse effects and higher dosage. Characterizing and understanding the basic physicochemical properties of pure active ingredients or technical grade active ingredients is critical, and our experts are committed to helping customers to evaluate and characterize their active ingredients. With extensive experience in handling multiple substances, we can help you perform both complex and simple testings according to your requirements.
Standard physicochemical testings for difficult-to-handle active ingredients
Some active ingredients are difficult to handle and require unique approaches. For example, some active ingredients with high volatility, low solubility, or requiring specific types of assays require tailored methods. We are experienced in providing a diversity of physicochemical testings for difficult-to-handle active ingredients:
- Analytical profile of the batches
- Appearance
- Boiling point
- Dissociation constants
- Henry's law constant
- Melting point/Freezing point
- Partition coefficient
- Relative density
- Spectra
- Surface tension
- Partition coefficient
- Vapor pressure
- Water solubility
Figure 1. Active ingredients of common household pesticides. (Pentamwa, P.; et al. 2011)
Characterization of the hazardous properties of active ingredients
- Explosivity properties
- Flammability studies
- Oxidation properties to UN 0.1 and 0.2
- Pyrophoric properties to UN N.2 and N.3
- Corrosiveness to metals
High-specification and wide range of analytical capabilities
- High performance liquid chromatography (UV, FLD, RI, MS, ELS, DAD)
- Gas chromatography (FID, NPD, ECD, FPD, MS)
- Infrared
- UV/Visible
- Molecular weight distribution
- Automatic titration
- Ion chromatography
- ICP-MS
- Nuclear Magnetic Resonance
BOC Sciences Advantages
- Highly specialized technical and analytical services for the worldwide registration and regulatory compliance of agrochemicals
- Robust analytical testing programs that span from research and product development through the production process to final product
- Relies on broad industrial experience, ensuring that all of our work meets the high standards expected by our clients
- Our regulatory experts, toxicology consultants, scientists and inspectors will ensure that you receive maximum levels of guidance, testing and inspection you need.
Reference
- Pentamwa, P.; et al. Indoor pesticide application practices and levels in homes of Bangkok Metropolitan Region. Environmental Monitoring & Assessment. 2011. 181(1-4): 363-372.