Agrochemicals Analytical Method Development & Validation
Analytical methods for agrochemicals must be validated to provide reliable data for regulatory submissions. These methods are essential for the following testing of stability samples, testing of active ingredients. Therefore, analytical method development and validation is an important part of the agrochemical development process to ensure that methods are well defined and fit-for-purpose, and the results generated are robust and reliable and that the product characteristics are in accordance with industry guidelines. At BOC Sciences, we can develop analytical methods to suit all your needs by using our laboratories equipped with state-of-the-art analytical instruments.
Figure 1. ToF-SIMS signal for fludioxonil molecular ion peak. (Converso, V.; et al. 2017)
Features of Our Services
- For the detection of active ingredients and any related impurities in agrochemicals, we validate the methods used in-house, taking into account the increasingly strict requirements of the authorities.
- We offer a wide range of single methods as well as impurity and trace metal validation for plant protection products, biocides, disinfectants, technical materials and various levels of formulated products.
- BOC Sciences is equipped with state-of-the-art instrumentation, and our analytical team has the experience to develop and validate efficient, accurate, reliable and robust analytical methods.
Method Development
- Our highly skilled method development scientists have years of experience with many types of agrochemical products, methods and analytical techniques to ensure successful results.
- We support any of your projects via using a wide range of methods and technologies to reliably and efficiently analyze major and partially unknown minor components of products as well as degradation products.
- The reliability of the analysis is ensured by performing the method validation to check the performance of the measurement method.
Method Validation
- Our analytical team has a comprehensive understanding of analytical method validation requirements that can be tailored to meet the requirements of different stages of agrochemical development.
- To ensure that methods meet regulatory requirements, we follow the relevant ICH guidelines in combination with customer-specific protocols.
Figure 2. Effect of different modifier compounds on the SIMS response to fludioxonil. (Converso, V.; et al. 2017)
Quality Requirements
- A good analysis does not start with sample preparation or measurement, but with understanding your problem. Thanks to their expertise and product knowledge, our experienced analysts are able to provide you with the best possible solution.
Wide Range of Analytical Techniques
- As one of the largest companies in the field of chemical analysis, we can offer a very broad range of methodologies. This allows us to guarantee a maximum flexibility and quality. For your any analytical problems, we can offer you qualified solutions and appropriate measurement techniques, from the ultra-trace range to the percentage range.
BOC Sciences Advantages
- Highly specialized technical and analytical services for the worldwide registration and regulatory compliance of agrochemicals
- Robust analytical testing programs that span from research and product development through the production process to final product
- Relies on broad industrial experience, ensuring that all of our work meets the high standards expected by our clients
- Our regulatory experts, toxicology consultants, scientists and inspectors will ensure that you receive maximum levels of guidance, testing and inspection you need.
Reference
- Converso, V.; et al. Analysis and imaging of biocidal agrochemicals using ToF-SIMS. Scientific Reports. 2017. 7(1): 10728.