Agrochemical Physical & Chemical Studies
Physicochemical testings of agrochemicals and the information they generate are essential for the registration of plant protection products and biocides in the all countries and regions. BOC Sciences can provide a comprehensive range of analysis methods for the determination of multiple physicochemical parameters, including those described in the OECD Guidelines for Testing of Chemicals and the CIPAC Handbook. Our multidisciplinary team of scientists can work with you to identify and provide the best combination of testings to meet your specific needs.
Figure 1. Active ingredients with different biological activities and MoA classifications. (Peter, J. 2016)
Application of Physico-Chemical Property Testing
- Predict toxicological or environmental hazards and behavior
- Assessment of risk to human health and the environment
- Risk management and safety handling purposes
Our Services
Active Ingredients Research
Formulated Products Research
Physico-Chemical Properties
- Melting point/melting range
- Boiling point/boiling range
- Density
- Vapour pressure
- Henry constant
- pH
- Physical state, colour and odour
- IR; NMR; GC/HPLC-MS; UV/VIS, ICP-MS
- Water solubility
- Solubility in organic solvents
- Partition coefficient
- Abiotic degradation / hydrolysis
- Dissociation constant
- Flammability (solids)
- Flash point (liquids)
- Flammability (solids)
- Bowes-Cameron cage testing
- Explosive properties
- Surface tension
- Oxidizing properties of solids
- Oxidizing properties of liquids
- Pyrophoric properties of solids and liquids
- Particle size distribution by laser diffraction
- Dilution stability of herbicide aqueous solution
- Degree of dissolution and solution stability
- Dispersion stability
- Particle size distribution
- Thermal stability
- Adsorption/desorption
- Auto-ignition temperatures of liquids or solids
- Acidity, alkalinity if pH is < 4 or >9
- Viscosity
- Surface tension
- Tap density / bulk density
- Wettability
- Persistent foaming
- Dispersibility of WG
- Suspensibility
- Spontaneity of dispersion
- Wet sieve test
- Dustiness
- Particle size distribution
- Friability and attrition characteristics
- Friability of tablets by using a Heubach Dustmeter
- Emulsion stability
- Flowability of WG after heat test under pressure
- Pourability
- Dilution stability of herbicide aqueous solution
- Degree of dissolution and solution stability
- Dissolution of water soluble bags
- Seed treatment/ loading analysis/ distribution and flow
- Effectiveness of cleaning procedures
Figure 2. Selective metabolism of acephate and malathion in insects in vivo. (Peter, J. 2016)
What We Offer
- Our physicochemical testing capabilities are delivered in either packaged form or as stand-alone tests.
- We can deliver these physical chemistries packages to Good Laboratory Practice (GLP) standards.
- We have particular expertise in the physicochemical testing requirements to provide comprehensive physicochemical property testing data.
- Our experts can offer physicochemical data for a wide range of agrochemicals, depending on the regulatory requirements for our customers' classification, labeling and packaging regulations.
- As part of the regulatory package, we also provide additional analytical characterization, GLP 5-batch analysis and impurity screening.
BOC Sciences Advantages
- Highly specialized technical and analytical services for the worldwide registration and regulatory compliance of agrochemicals
- Robust analytical testing programs that span from research and product development through the production process to final product
- Relies on broad industrial experience, ensuring that all of our work meets the high standards expected by our clients
- Our regulatory experts, toxicology consultants, scientists and inspectors will ensure that you receive maximum levels of guidance, testing and inspection you need.
Reference
- Peter, J. Propesticides and their use as agrochemicals. Pest Management Science. 2016. 72(2): 210-225.